“I’m Fed Up Arnold and I Don’t Care Who Knows It.”

(,“I’m Fed Up Arnold and I Don’t Care Who Knows It.” - Arnold Horshack
 
There was a scene from the 1975-1979 Classic TV Sitcom ”Welcome Back Kotter” where Arnold Horshack is on the class Radio show and he gives a moving monologue about being fed up with Reality.  He tells his listeners that if they feel the same way as he does to go to the window and yell out to the city, “I’m fed up Arnold and I don’t care who knows It.”
 
Arnold goes to the window and yells out “I’m fed up Arnold and I don’t care who knows It.”  Long dramatic silent pause.  And then a distant “I’m fed up Arnold and I don’t care who knows It.” And another, “I’m fed up Arnold and I don’t care who knows It.”  And Arnold feels better because he isn’t alone. 
 
Here is an article that Dr. Rouzbeh Taghizadeh wrote most of and I contributed enough of the content to be listed as an author. This was our company Auxocell Laboratories, Inc. position paper in 2010 that was published in the International Society for Cell and Gene Therapy (ISCT) Newsletter.   

In 2010, Osiris Therapeutics was about to be approved as the world’s first stem cell therapy in Canada (2012) and then New Zealand (2012) and it was to usher in the golden and marvelous age of stem cell therapy.  This drug is a last line of defense for children who undergo cancer treatments and then their body rejects the stem cell treatment to restore their immune system.  The approved approach of steroid treatment fails leaving the child with a 90% mortality rate.  This drug now is called Remestemcel-L and Remestmyal is still not approved in the US when write this In April 2024. (See Remestemcel-L Powerpoint Presentation)
 
The tiny incremental advances to the clinic and patients make me want to go to my window and yell “I’m fed up Arnold and I don’t care who knows It,” right now.      
 
Today, I am even more solidly convinced 14 years later that Perinatal derived stem cell, tissue and exosome therapies will be the most efficacious, safest, easiest to administer as well as the most cost-effective source of stem cells
 
Please help me to correct the regulatory framework our society has accepted as the only way to regulate these incredible stem cells and tissue products and allow access to stem cell therapy in the US.   Help me to change the law!